Keeping the appeal of a young-looking skin with increasing age has always been the desire of women and men. But in reality they face reduced skin elasticity, poorer structure and appearance of wrinkles. An important part of those skin changes is caused by a reduced turnover of skin cells and exposure to environmental factors such as UV light. It is recognized that especially the more deeply penetrating UVA light triggers cutaneous photo-aging by a pathway that starts in dermal fibroblasts with alterations of mitochondrial DNA. A strategy helping to slow-down premature skin-aging would therefore involve stimulation of skin cells such as fibroblasts, while preventing DNA damages at the same time.
Studies with cultured human fibroblasts showed that Folic Acid (also known as Vitamin B9, Vitamin M or Vitamin Bc) promotes the growth of fibroblasts and stimulates the division of both young and mature fibroblasts growing either in standard medium or under nutrient deficiency. Microscopic observation further reveals that the fibroblasts were more regular in shape (spindle-shaped) compared to non-Folic Acid treated cells.
An essential factor for regenerating processes in dermal and epidermal skin cells, Folic Acid is a highly recommended for skincare and suncare products to help prevent signs of aging and photo-aging.